Publications / Presentations


Neuropsychiatry / Neurology

Pulications

  • Schizophrenia Research 2017 [Epub ahead of print]

Dopamine Serotonin Stabilizer RP5063: A Randomized, Double-blind, Placebo-controlled Multicenter Trial of Safety and Efficacy in Exacerbation of Schizophrenia or Schizoaffective Disorder

Marc Cantillon, Arulprakash R, Ajay Alexander, Robert Ings, Dennis Sweitzer, Laxminarayan Bhat

  • Behavioral Brain Research 2017 [Epub ahead of print]

RP5063, an atypical antipsychotic drug with a novel mechanism of action, improves cognition and psychosis in mouse models of schizophrenia

Lakshmi Rajagopal, Sunoh Kwon, Mei Huang, Eric Michael, Laxminaryan Bhat, Marc Cantillon, Herbert Y. Meltzer;

 

Presentations

  • Society for Neuroscience Annual Meeting, Chicago, USA. October 17-21, 2015

RP5063 reverses and prevents subchronic phencyclidine-induced declarative memory deficits and increases cortical dopamine in C57BL/6J mice.

Kwon S. et al.

  • New Clinical Drug Evaluation Unit (NCDEU) Conference, Hollywood, Florida, USA. May 29, 2013.

RP5063 safety and efficacy in schizophrenia and schizoaffective disorder.

Cantillon M. et al.

  • New Clinical Drug Evaluation Unit (NCDEU) Conference, Phoenix, Arizona, USA. May 30, 2012.

RP5063 safety, pharmacokinetics and pharmacodynamics in schizophrenia.

Cantillon M. et al

 

 

Pulmonary Arterial Hypertension / Cardiopulmonology

Pulications

  • European J Pharmacology 2017 [Epub ahead of print]

RP5063, a novel, multimodal, serotonin receptor modulator, prevents Sugen 5416-induced pulmonary arterial hypertension in rats.

Laxminarayan Bhat, Jon Hawkinson, Marc Cantillon, Dasharatha G Reddy, Seema R Bhat, Charles E. Laurent, Annie Bouchard, Marzena Biernat, and Dany Salvail.

  • European J Pharmacology 2017 [Epub ahead of print]

RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats.

Laxminarayan Bhat, Jon Hawkinson, Marc Cantillon, Dasharatha G Reddy, Seema R Bhat, Charles E. Laurent, Annie Bouchard, Marzena Biernat, and Dany Salvail.

 

Presentations

  • American Thoracic Society (ATS) International Conference, Washington DC, USA. May 19-24, 2017.

RP5063 mitigates the developments and severity of sugen-hypoxia induced pulmonary arterial hypertension in rats.

Bhat L. et al

  • American Thoracic Society (ATS) International Conference, San Francisco, USA. May 13-18, 2016

RP5063 prevents moncrotaline-induced pulmonary arterial hypertension in rats.

Bhat L. et al

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